Does DENOSUMAB Cause Nephrolithiasis? 343 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 343 reports of Nephrolithiasis have been filed in association with DENOSUMAB (Bilprevda). This represents 0.2% of all adverse event reports for DENOSUMAB.
343
Reports of Nephrolithiasis with DENOSUMAB
0.2%
of all DENOSUMAB reports
4
Deaths
93
Hospitalizations
How Dangerous Is Nephrolithiasis From DENOSUMAB?
Of the 343 reports, 4 (1.2%) resulted in death, 93 (27.1%) required hospitalization, and 8 (2.3%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DENOSUMAB. However, 343 reports have been filed with the FAERS database.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which DENOSUMAB Alternatives Have Lower Nephrolithiasis Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE