Does DEXRAZOXANE Cause Myelosuppression? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Myelosuppression have been filed in association with DEXRAZOXANE (Dexrazoxane). This represents 4.5% of all adverse event reports for DEXRAZOXANE.
51
Reports of Myelosuppression with DEXRAZOXANE
4.5%
of all DEXRAZOXANE reports
10
Deaths
25
Hospitalizations
How Dangerous Is Myelosuppression From DEXRAZOXANE?
Of the 51 reports, 10 (19.6%) resulted in death, 25 (49.0%) required hospitalization, and 10 (19.6%) were considered life-threatening.
Is Myelosuppression Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXRAZOXANE. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does DEXRAZOXANE Cause?
Febrile neutropenia (315)
Off label use (266)
Clostridium difficile colitis (91)
Cellulitis (84)
Product use in unapproved indication (84)
Pyrexia (81)
Fungal infection (74)
Bacterial infection (73)
Lymphoid tissue hypoplasia (72)
Lymphopenia (70)
What Other Drugs Cause Myelosuppression?
CYCLOPHOSPHAMIDE (3,603)
CARBOPLATIN (2,624)
TRASTUZUMAB (2,552)
PACLITAXEL (2,522)
TISLELIZUMAB (2,142)
CYTARABINE (1,869)
VENETOCLAX (1,864)
CISPLATIN (1,849)
BEVACIZUMAB (1,744)
SODIUM (1,696)
Which DEXRAZOXANE Alternatives Have Lower Myelosuppression Risk?
DEXRAZOXANE vs DEXTRAN 70\HYPROMELLOSE 2910
DEXRAZOXANE vs DEXTROAMPHETAMINE
DEXRAZOXANE vs DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE AND AMPHETAMINE
DEXRAZOXANE vs DEXTROMETHORPHAN
DEXRAZOXANE vs DEXTROMETHORPHAN HYDROBROMIDE