Does DEXRAZOXANE Cause Thymus hypoplasia? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Thymus hypoplasia have been filed in association with DEXRAZOXANE (Dexrazoxane). This represents 6.2% of all adverse event reports for DEXRAZOXANE.
70
Reports of Thymus hypoplasia with DEXRAZOXANE
6.2%
of all DEXRAZOXANE reports
6
Deaths
70
Hospitalizations
How Dangerous Is Thymus hypoplasia From DEXRAZOXANE?
Of the 70 reports, 6 (8.6%) resulted in death, 70 (100.0%) required hospitalization.
Is Thymus hypoplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXRAZOXANE. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does DEXRAZOXANE Cause?
Febrile neutropenia (315)
Off label use (266)
Clostridium difficile colitis (91)
Cellulitis (84)
Product use in unapproved indication (84)
Pyrexia (81)
Fungal infection (74)
Bacterial infection (73)
Lymphoid tissue hypoplasia (72)
Lymphopenia (70)
What Other Drugs Cause Thymus hypoplasia?
CYCLOPHOSPHAMIDE (148)
CYTARABINE (148)
DAUNORUBICIN (148)
DEXAMETHASONE (148)
ETOPOSIDE (148)
FILGRASTIM (144)
CYCLOSPORINE (111)
MERCAPTOPURINE (84)
METHOTREXATE (84)
METHYLPREDNISOLONE (84)
Which DEXRAZOXANE Alternatives Have Lower Thymus hypoplasia Risk?
DEXRAZOXANE vs DEXTRAN 70\HYPROMELLOSE 2910
DEXRAZOXANE vs DEXTROAMPHETAMINE
DEXRAZOXANE vs DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE AND AMPHETAMINE
DEXRAZOXANE vs DEXTROMETHORPHAN
DEXRAZOXANE vs DEXTROMETHORPHAN HYDROBROMIDE