Thymus hypoplasia: Which Medications Cause It? (164 Reports Across 29 Drugs)
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Thymus hypoplasia has been reported as an adverse event with 29 different drugs in the FDA's FAERS database, with 164 total reports. 96 of these reports resulted in death.The drugs most commonly associated with Thymus hypoplasia are CYCLOPHOSPHAMIDE, CYTARABINE, and DAUNORUBICIN.
164
Total Reports
29
Drugs Involved
96
Deaths
74
Hospitalizations
24.4 yrs
Average Patient Age
7.6% / 92.4%
Female / Male
Which Drugs Cause Thymus hypoplasia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CYCLOPHOSPHAMIDE | 148 | 0.1% | 84 | 70 | 0 |
| CYTARABINE | 148 | 0.3% | 84 | 70 | 0 |
| DAUNORUBICIN | 148 | 1.5% | 84 | 70 | 0 |
| DEXAMETHASONE | 148 | 0.1% | 84 | 70 | 0 |
| ETOPOSIDE | 148 | 0.3% | 84 | 70 | 0 |
| FILGRASTIM | 144 | 1.0% | 80 | 70 | 0 |
| CYCLOSPORINE | 111 | 0.2% | 49 | 68 | 0 |
| MERCAPTOPURINE | 84 | 0.7% | 84 | 6 | 0 |
| METHOTREXATE | 84 | 0.0% | 84 | 6 | 0 |
| METHYLPREDNISOLONE | 84 | 0.1% | 84 | 6 | 0 |
| PEGASPARGASE | 84 | 0.7% | 84 | 6 | 0 |
| PREDNISONE | 84 | 0.1% | 84 | 6 | 0 |
| VINCRISTINE | 83 | 0.1% | 83 | 6 | 0 |
| ASPARAGINASE | 80 | 1.6% | 80 | 6 | 0 |
| HYDROCORTISONE | 71 | 0.3% | 71 | 6 | 0 |
| ALLOPURINOL | 70 | 0.4% | 6 | 70 | 0 |
| CEFAZOLIN | 70 | 1.4% | 6 | 70 | 0 |
| CHOLECALCIFEROL | 70 | 0.6% | 6 | 70 | 0 |
| DEXRAZOXANE | 70 | 6.2% | 6 | 70 | 0 |
| FUROSEMIDE | 70 | 0.1% | 6 | 70 | 0 |