Does ASPARAGINASE Cause Thymus hypoplasia? 80 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 80 reports of Thymus hypoplasia have been filed in association with ASPARAGINASE (Rylaze). This represents 1.6% of all adverse event reports for ASPARAGINASE.
80
Reports of Thymus hypoplasia with ASPARAGINASE
1.6%
of all ASPARAGINASE reports
80
Deaths
6
Hospitalizations
How Dangerous Is Thymus hypoplasia From ASPARAGINASE?
Of the 80 reports, 80 (100.0%) resulted in death, 6 (7.5%) required hospitalization.
Is Thymus hypoplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 80 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
What Other Drugs Cause Thymus hypoplasia?
CYCLOPHOSPHAMIDE (148)
CYTARABINE (148)
DAUNORUBICIN (148)
DEXAMETHASONE (148)
ETOPOSIDE (148)
FILGRASTIM (144)
CYCLOSPORINE (111)
MERCAPTOPURINE (84)
METHOTREXATE (84)
METHYLPREDNISOLONE (84)
Which ASPARAGINASE Alternatives Have Lower Thymus hypoplasia Risk?
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ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
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ASPARAGINASE vs ASPIRIN LYSINE