Does ASPARAGINASE Cause Neutropenia? 322 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 322 reports of Neutropenia have been filed in association with ASPARAGINASE (Rylaze). This represents 6.5% of all adverse event reports for ASPARAGINASE.
322
Reports of Neutropenia with ASPARAGINASE
6.5%
of all ASPARAGINASE reports
50
Deaths
130
Hospitalizations
How Dangerous Is Neutropenia From ASPARAGINASE?
Of the 322 reports, 50 (15.5%) resulted in death, 130 (40.4%) required hospitalization, and 68 (21.1%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for ASPARAGINASE.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Clostridium difficile colitis (213)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
Posterior reversible encephalopathy syndrome (195)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which ASPARAGINASE Alternatives Have Lower Neutropenia Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE