Does ASPARAGINASE Cause Sepsis? 200 Reports in FDA Database

Q: Does ASPARAGINASE cause Sepsis?

200 reports of Sepsis have been filed with the FDA for ASPARAGINASE, representing 4.0% of all ASPARAGINASE adverse event reports.

Q: How dangerous is Sepsis from ASPARAGINASE?

Of 200 reports, 95 (47.5%) resulted in death and 70 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 200 reports of Sepsis have been filed in association with ASPARAGINASE (Rylaze). This represents 4.0% of all adverse event reports for ASPARAGINASE.

200

Reports of Sepsis with ASPARAGINASE

4.0%

of all ASPARAGINASE reports

Deaths

Hospitalizations

How Dangerous Is Sepsis From ASPARAGINASE?

Of the 200 reports, 95 (47.5%) resulted in death, 70 (35.0%) required hospitalization, and 45 (22.5%) were considered life-threatening.

Is Sepsis Listed in the Official Label?

Yes, Sepsis is listed as a known adverse reaction in the official FDA drug label for ASPARAGINASE.

What Other Side Effects Does ASPARAGINASE Cause?

Febrile neutropenia (557) Neutropenia (322) Bacterial infection (295) Off label use (267) Secondary immunodeficiency (233) Viral infection (228) Clostridium difficile colitis (213) Pyrexia (204) Pneumonia (196) Posterior reversible encephalopathy syndrome (195)

What Other Drugs Cause Sepsis?

RITUXIMAB (4,043) CYCLOPHOSPHAMIDE (4,041) METHOTREXATE (3,933) ADALIMUMAB (3,169) DEXAMETHASONE (3,150) LENALIDOMIDE (2,956) VINCRISTINE (2,791) DOXORUBICIN (2,740) PREDNISONE (2,634) PREDNISOLONE (2,281)

Which ASPARAGINASE Alternatives Have Lower Sepsis Risk?

ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN ASPARAGINASE vs ASPIRIN ASPARAGINASE vs ASPIRIN DL-LYSINE ASPARAGINASE vs ASPIRIN LYSINE

ASPARAGINASE Full Profile All Sepsis Reports All Drugs Causing Sepsis ASPARAGINASE Demographics