Does ASPARAGINASE Cause Clostridium difficile colitis? 213 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 213 reports of Clostridium difficile colitis have been filed in association with ASPARAGINASE (Rylaze). This represents 4.3% of all adverse event reports for ASPARAGINASE.
213
Reports of Clostridium difficile colitis with ASPARAGINASE
4.3%
of all ASPARAGINASE reports
201
Deaths
16
Hospitalizations
How Dangerous Is Clostridium difficile colitis From ASPARAGINASE?
Of the 213 reports, 201 (94.4%) resulted in death, 16 (7.5%) required hospitalization, and 6 (2.8%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPARAGINASE. However, 213 reports have been filed with the FAERS database.
What Other Side Effects Does ASPARAGINASE Cause?
Febrile neutropenia (557)
Neutropenia (322)
Bacterial infection (295)
Off label use (267)
Secondary immunodeficiency (233)
Viral infection (228)
Pyrexia (204)
Sepsis (200)
Pneumonia (196)
Posterior reversible encephalopathy syndrome (195)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which ASPARAGINASE Alternatives Have Lower Clostridium difficile colitis Risk?
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI
ASPARAGINASE vs ASPARAGINASE ERWINIA CHRYSANTHEMI -RYWN
ASPARAGINASE vs ASPIRIN
ASPARAGINASE vs ASPIRIN DL-LYSINE
ASPARAGINASE vs ASPIRIN LYSINE