Does METHOTREXATE Cause Sepsis? 3,933 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,933 reports of Sepsis have been filed in association with METHOTREXATE (Methotrexate). This represents 1.6% of all adverse event reports for METHOTREXATE.
3,933
Reports of Sepsis with METHOTREXATE
1.6%
of all METHOTREXATE reports
1,508
Deaths
2,278
Hospitalizations
How Dangerous Is Sepsis From METHOTREXATE?
Of the 3,933 reports, 1,508 (38.3%) resulted in death, 2,278 (57.9%) required hospitalization, and 852 (21.7%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
Yes, Sepsis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
ETOPOSIDE (2,211)
Which METHOTREXATE Alternatives Have Lower Sepsis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA