Does PEGASPARGASE Cause Thymus hypoplasia? 84 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 84 reports of Thymus hypoplasia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.7% of all adverse event reports for PEGASPARGASE.
84
Reports of Thymus hypoplasia with PEGASPARGASE
0.7%
of all PEGASPARGASE reports
84
Deaths
6
Hospitalizations
How Dangerous Is Thymus hypoplasia From PEGASPARGASE?
Of the 84 reports, 84 (100.0%) resulted in death, 6 (7.1%) required hospitalization.
Is Thymus hypoplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 84 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Thymus hypoplasia?
CYCLOPHOSPHAMIDE (148)
CYTARABINE (148)
DAUNORUBICIN (148)
DEXAMETHASONE (148)
ETOPOSIDE (148)
FILGRASTIM (144)
CYCLOSPORINE (111)
MERCAPTOPURINE (84)
METHOTREXATE (84)
METHYLPREDNISOLONE (84)
Which PEGASPARGASE Alternatives Have Lower Thymus hypoplasia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ