Does PEGASPARGASE Cause Neutropenia? 521 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 521 reports of Neutropenia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 4.5% of all adverse event reports for PEGASPARGASE.
521
Reports of Neutropenia with PEGASPARGASE
4.5%
of all PEGASPARGASE reports
84
Deaths
391
Hospitalizations
How Dangerous Is Neutropenia From PEGASPARGASE?
Of the 521 reports, 84 (16.1%) resulted in death, 391 (75.0%) required hospitalization, and 77 (14.8%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for PEGASPARGASE.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
Nausea (370)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which PEGASPARGASE Alternatives Have Lower Neutropenia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ