Does PEGASPARGASE Cause Sepsis? 548 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 548 reports of Sepsis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 4.8% of all adverse event reports for PEGASPARGASE.
548
Reports of Sepsis with PEGASPARGASE
4.8%
of all PEGASPARGASE reports
158
Deaths
416
Hospitalizations
How Dangerous Is Sepsis From PEGASPARGASE?
Of the 548 reports, 158 (28.8%) resulted in death, 416 (75.9%) required hospitalization, and 111 (20.3%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
Yes, Sepsis is listed as a known adverse reaction in the official FDA drug label for PEGASPARGASE.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
Nausea (370)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which PEGASPARGASE Alternatives Have Lower Sepsis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ