Does PEGASPARGASE Cause Hypertriglyceridaemia? 399 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 399 reports of Hypertriglyceridaemia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 3.5% of all adverse event reports for PEGASPARGASE.
399
Reports of Hypertriglyceridaemia with PEGASPARGASE
3.5%
of all PEGASPARGASE reports
29
Deaths
179
Hospitalizations
How Dangerous Is Hypertriglyceridaemia From PEGASPARGASE?
Of the 399 reports, 29 (7.3%) resulted in death, 179 (44.9%) required hospitalization, and 35 (8.8%) were considered life-threatening.
Is Hypertriglyceridaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 399 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypotension (388)
Thrombocytopenia (382)
Nausea (370)
What Other Drugs Cause Hypertriglyceridaemia?
VINCRISTINE (373)
METHOTREXATE (372)
DEXAMETHASONE (358)
CYTARABINE (244)
CYCLOPHOSPHAMIDE (191)
QUETIAPINE (181)
MERCAPTOPURINE (176)
PREDNISONE (161)
DAUNORUBICIN (143)
DOXORUBICIN (140)
Which PEGASPARGASE Alternatives Have Lower Hypertriglyceridaemia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ