Does PEGASPARGASE Cause Thrombocytopenia? 382 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 382 reports of Thrombocytopenia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 3.3% of all adverse event reports for PEGASPARGASE.
382
Reports of Thrombocytopenia with PEGASPARGASE
3.3%
of all PEGASPARGASE reports
59
Deaths
269
Hospitalizations
How Dangerous Is Thrombocytopenia From PEGASPARGASE?
Of the 382 reports, 59 (15.4%) resulted in death, 269 (70.4%) required hospitalization, and 60 (15.7%) were considered life-threatening.
Is Thrombocytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 382 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Nausea (370)
What Other Drugs Cause Thrombocytopenia?
DEXAMETHASONE (5,873)
RITUXIMAB (4,810)
CYCLOPHOSPHAMIDE (4,669)
LENALIDOMIDE (4,584)
CARBOPLATIN (4,483)
METHOTREXATE (3,865)
DOXORUBICIN (3,638)
ETOPOSIDE (3,085)
VINCRISTINE (2,940)
OXALIPLATIN (2,886)
Which PEGASPARGASE Alternatives Have Lower Thrombocytopenia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ