Does DORNASE ALFA Cause Ascites? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Ascites have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.4% of all adverse event reports for DORNASE ALFA.
20
Reports of Ascites with DORNASE ALFA
0.4%
of all DORNASE ALFA reports
20
Deaths
19
Hospitalizations
How Dangerous Is Ascites From DORNASE ALFA?
Of the 20 reports, 20 (100.0%) resulted in death, 19 (95.0%) required hospitalization, and 20 (100.0%) were considered life-threatening.
Is Ascites Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Ascites?
BEVACIZUMAB (1,067)
RIBAVIRIN (1,025)
TREPROSTINIL (672)
ACETAMINOPHEN (599)
SOFOSBUVIR (598)
PACLITAXEL (581)
LETROZOLE (579)
CYCLOPHOSPHAMIDE (561)
OXALIPLATIN (533)
METHOTREXATE (521)
Which DORNASE ALFA Alternatives Have Lower Ascites Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68