Does DORNASE ALFA Cause Bronchospasm? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Bronchospasm have been filed in association with DORNASE ALFA (Pulmozyme). This represents 1.3% of all adverse event reports for DORNASE ALFA.
70
Reports of Bronchospasm with DORNASE ALFA
1.3%
of all DORNASE ALFA reports
0
Deaths
64
Hospitalizations
How Dangerous Is Bronchospasm From DORNASE ALFA?
Of the 70 reports, 64 (91.4%) required hospitalization.
Is Bronchospasm Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Bronchospasm?
ALBUTEROL (431)
OXALIPLATIN (422)
OMALIZUMAB (370)
PROPOFOL (356)
PACLITAXEL (333)
ROCURONIUM (252)
MEPOLIZUMAB (249)
IBUPROFEN (203)
ACETAMINOPHEN (195)
CARBOPLATIN (188)
Which DORNASE ALFA Alternatives Have Lower Bronchospasm Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68