Does DORNASE ALFA Cause Cardiac arrest? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Cardiac arrest have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.1% of all adverse event reports for DORNASE ALFA.
6
Reports of Cardiac arrest with DORNASE ALFA
0.1%
of all DORNASE ALFA reports
3
Deaths
1
Hospitalizations
How Dangerous Is Cardiac arrest From DORNASE ALFA?
Of the 6 reports, 3 (50.0%) resulted in death, 1 (16.7%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Cardiac arrest Listed in the Official Label?
Yes, Cardiac arrest is listed as a known adverse reaction in the official FDA drug label for DORNASE ALFA.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Cardiac arrest?
FENTANYL (1,711)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (1,336)
ALPRAZOLAM (1,252)
OXYCODONE (1,234)
METFORMIN (1,209)
SACUBITRIL\VALSARTAN (1,108)
BUPROPION (1,028)
ACETAMINOPHEN (947)
QUETIAPINE (931)
MORPHINE (803)
Which DORNASE ALFA Alternatives Have Lower Cardiac arrest Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68