Does DORNASE ALFA Cause Increased bronchial secretion? 39 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 39 reports of Increased bronchial secretion have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.7% of all adverse event reports for DORNASE ALFA.
39
Reports of Increased bronchial secretion with DORNASE ALFA
0.7%
of all DORNASE ALFA reports
27
Deaths
33
Hospitalizations
How Dangerous Is Increased bronchial secretion From DORNASE ALFA?
Of the 39 reports, 27 (69.2%) resulted in death, 33 (84.6%) required hospitalization, and 25 (64.1%) were considered life-threatening.
Is Increased bronchial secretion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 39 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Increased bronchial secretion?
ALBUTEROL (637)
OMALIZUMAB (144)
MEPOLIZUMAB (119)
FLUTICASONE FUROATE\UMECLIDINIUM\VILANTEROL TRIFENATATE (93)
FLUTICASONE FUROATE\VILANTEROL TRIFENATATE (87)
FLUTICASONE\SALMETEROL (86)
FLUTICASONE (82)
PREDNISONE (74)
TIOTROPIUM (65)
BUDESONIDE\FORMOTEROL (63)
Which DORNASE ALFA Alternatives Have Lower Increased bronchial secretion Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68