Does DORNASE ALFA Cause Pneumococcal sepsis? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Pneumococcal sepsis have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.5% of all adverse event reports for DORNASE ALFA.
27
Reports of Pneumococcal sepsis with DORNASE ALFA
0.5%
of all DORNASE ALFA reports
26
Deaths
26
Hospitalizations
How Dangerous Is Pneumococcal sepsis From DORNASE ALFA?
Of the 27 reports, 26 (96.3%) resulted in death, 26 (96.3%) required hospitalization, and 26 (96.3%) were considered life-threatening.
Is Pneumococcal sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DORNASE ALFA. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Pneumococcal sepsis?
DEXAMETHASONE (52)
CYCLOPHOSPHAMIDE (30)
ALBUTEROL (29)
PIPERACILLIN\TAZOBACTAM (29)
CIPROFLOXACIN (28)
LENALIDOMIDE (28)
PENICILLIN G (28)
FENTANYL (27)
GENTAMICIN (27)
MEROPENEM (27)
Which DORNASE ALFA Alternatives Have Lower Pneumococcal sepsis Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68