Does DORNASE ALFA Cause Respiratory failure? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Respiratory failure have been filed in association with DORNASE ALFA (Pulmozyme). This represents 0.6% of all adverse event reports for DORNASE ALFA.
33
Reports of Respiratory failure with DORNASE ALFA
0.6%
of all DORNASE ALFA reports
19
Deaths
21
Hospitalizations
How Dangerous Is Respiratory failure From DORNASE ALFA?
Of the 33 reports, 19 (57.6%) resulted in death, 21 (63.6%) required hospitalization, and 2 (6.1%) were considered life-threatening.
Is Respiratory failure Listed in the Official Label?
Yes, Respiratory failure is listed as a known adverse reaction in the official FDA drug label for DORNASE ALFA.
What Other Side Effects Does DORNASE ALFA Cause?
No adverse event (889)
Cystic fibrosis (565)
Off label use (522)
Hospitalisation (512)
Pneumonia (377)
Condition aggravated (304)
Dyspnoea (246)
Infective pulmonary exacerbation of cystic fibrosis (245)
Product storage error (242)
Death (225)
What Other Drugs Cause Respiratory failure?
PREDNISONE (2,299)
CYCLOPHOSPHAMIDE (2,096)
RITUXIMAB (1,838)
TACROLIMUS (1,758)
METHOTREXATE (1,685)
DEXAMETHASONE (1,603)
MYCOPHENOLATE MOFETIL (1,469)
METHYLPREDNISOLONE (1,442)
PREDNISOLONE (1,346)
VINCRISTINE (1,120)
Which DORNASE ALFA Alternatives Have Lower Respiratory failure Risk?
DORNASE ALFA vs DORZOLAMIDE
DORNASE ALFA vs DORZOLAMIDE\TIMOLOL
DORNASE ALFA vs DOSTARLIMAB
DORNASE ALFA vs DOSTARLIMAB-GXLY
DORNASE ALFA vs DOTATATE GALLIUM GA-68