Does DUPILUMAB Cause Nephrolithiasis? 427 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 427 reports of Nephrolithiasis have been filed in association with DUPILUMAB (Dupixent). This represents 0.1% of all adverse event reports for DUPILUMAB.
427
Reports of Nephrolithiasis with DUPILUMAB
0.1%
of all DUPILUMAB reports
1
Deaths
142
Hospitalizations
How Dangerous Is Nephrolithiasis From DUPILUMAB?
Of the 427 reports, 1 (0.2%) resulted in death, 142 (33.3%) required hospitalization, and 1 (0.2%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DUPILUMAB. However, 427 reports have been filed with the FAERS database.
What Other Side Effects Does DUPILUMAB Cause?
Pruritus (44,279)
Dermatitis atopic (33,670)
Product use in unapproved indication (33,452)
Rash (30,895)
Injection site pain (27,799)
Drug ineffective (23,712)
Dry skin (20,239)
Eczema (20,020)
Product dose omission issue (18,189)
Condition aggravated (16,459)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which DUPILUMAB Alternatives Have Lower Nephrolithiasis Risk?
DUPILUMAB vs DURAGESIC
DUPILUMAB vs DUROGESIC
DUPILUMAB vs DUROTEP MT
DUPILUMAB vs DURVALUMAB
DUPILUMAB vs DUTASTERIDE