Does ECULIZUMAB Cause Cytopenia? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Cytopenia have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
58
Reports of Cytopenia with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
4
Deaths
15
Hospitalizations
How Dangerous Is Cytopenia From ECULIZUMAB?
Of the 58 reports, 4 (6.9%) resulted in death, 15 (25.9%) required hospitalization, and 19 (32.8%) were considered life-threatening.
Is Cytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Cytopenia?
RITUXIMAB (1,372)
LENALIDOMIDE (1,252)
DEXAMETHASONE (1,193)
CYCLOPHOSPHAMIDE (1,191)
VENETOCLAX (1,019)
METHOTREXATE (955)
ETOPOSIDE (854)
CARBOPLATIN (754)
DOXORUBICIN (709)
VINCRISTINE (648)
Which ECULIZUMAB Alternatives Have Lower Cytopenia Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB