Does METHOTREXATE Cause Cytopenia? 955 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 955 reports of Cytopenia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
955
Reports of Cytopenia with METHOTREXATE
0.4%
of all METHOTREXATE reports
64
Deaths
205
Hospitalizations
How Dangerous Is Cytopenia From METHOTREXATE?
Of the 955 reports, 64 (6.7%) resulted in death, 205 (21.5%) required hospitalization, and 68 (7.1%) were considered life-threatening.
Is Cytopenia Listed in the Official Label?
Yes, Cytopenia is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Cytopenia?
RITUXIMAB (1,372)
LENALIDOMIDE (1,252)
DEXAMETHASONE (1,193)
CYCLOPHOSPHAMIDE (1,191)
VENETOCLAX (1,019)
ETOPOSIDE (854)
CARBOPLATIN (754)
DOXORUBICIN (709)
VINCRISTINE (648)
PREDNISONE (558)
Which METHOTREXATE Alternatives Have Lower Cytopenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA