Does ECULIZUMAB Cause Fluid overload? 140 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 140 reports of Fluid overload have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.3% of all adverse event reports for ECULIZUMAB.
140
Reports of Fluid overload with ECULIZUMAB
0.3%
of all ECULIZUMAB reports
23
Deaths
110
Hospitalizations
How Dangerous Is Fluid overload From ECULIZUMAB?
Of the 140 reports, 23 (16.4%) resulted in death, 110 (78.6%) required hospitalization, and 8 (5.7%) were considered life-threatening.
Is Fluid overload Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 140 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Fluid overload?
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (3,883)
TREPROSTINIL (1,239)
DIANEAL LOW (831)
MACITENTAN (809)
AMBRISENTAN (764)
EPOPROSTENOL (496)
CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM (493)
SELEXIPAG (294)
RIOCIGUAT (198)
BOSENTAN (168)
Which ECULIZUMAB Alternatives Have Lower Fluid overload Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB