Fluid overload: Which Medications Cause It? (11,271 Reports Across 292 Drugs)
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Fluid overload has been reported as an adverse event with 292 different drugs in the FDA's FAERS database, with 11,271 total reports. 1,456 of these reports resulted in death.The drugs most commonly associated with Fluid overload are CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM, TREPROSTINIL, and DIANEAL LOW.
11,271
Total Reports
292
Drugs Involved
1,456
Deaths
7,334
Hospitalizations
58.7 yrs
Average Patient Age
57.1% / 42.9%
Female / Male
Which Drugs Cause Fluid overload Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM | 3,883 | 4.1% | 117 | 1,495 | 13 |
| TREPROSTINIL | 1,239 | 1.4% | 173 | 1,190 | 43 |
| DIANEAL LOW | 831 | 7.4% | 20 | 264 | 0 |
| MACITENTAN | 809 | 1.8% | 288 | 774 | 42 |
| AMBRISENTAN | 764 | 0.9% | 97 | 687 | 20 |
| EPOPROSTENOL | 496 | 3.7% | 193 | 492 | 26 |
| CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM | 493 | 2.5% | 28 | 225 | 2 |
| SELEXIPAG | 294 | 1.6% | 85 | 283 | 8 |
| RIOCIGUAT | 198 | 1.1% | 49 | 187 | 4 |
| BOSENTAN | 168 | 0.9% | 59 | 157 | 13 |
| ECULIZUMAB | 140 | 0.3% | 23 | 110 | 8 |
| FUROSEMIDE | 127 | 0.2% | 21 | 99 | 17 |
| TADALAFIL | 123 | 0.4% | 27 | 112 | 8 |
| SACUBITRIL\VALSARTAN | 121 | 0.1% | 7 | 89 | 4 |
| LENALIDOMIDE | 118 | 0.0% | 7 | 85 | 1 |
| PREDNISONE | 118 | 0.1% | 22 | 103 | 21 |
| DEXAMETHASONE | 115 | 0.1% | 23 | 87 | 19 |
| SILDENAFIL | 113 | 0.3% | 28 | 94 | 7 |
| EXTRANEAL | 105 | 5.3% | 5 | 47 | 0 |
| TACROLIMUS | 101 | 0.1% | 13 | 81 | 12 |
Top 3 Drugs Associated With Fluid overload
3,883 reports
1,239 reports
831 reports