Does ECULIZUMAB Cause Immunodeficiency? 61 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Immunodeficiency have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
61
Reports of Immunodeficiency with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
7
Deaths
32
Hospitalizations
How Dangerous Is Immunodeficiency From ECULIZUMAB?
Of the 61 reports, 7 (11.5%) resulted in death, 32 (52.5%) required hospitalization, and 1 (1.6%) were considered life-threatening.
Is Immunodeficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 61 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Immunodeficiency?
ADALIMUMAB (2,981)
RITUXIMAB (1,256)
TOCILIZUMAB (1,061)
ABATACEPT (1,042)
METHOTREXATE (926)
ETANERCEPT (799)
INFLIXIMAB (693)
CETIRIZINE (650)
METHYLPREDNISOLONE (615)
ALBUTEROL (599)
Which ECULIZUMAB Alternatives Have Lower Immunodeficiency Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB