Does ECULIZUMAB Cause Iron overload? 137 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 137 reports of Iron overload have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.3% of all adverse event reports for ECULIZUMAB.
137
Reports of Iron overload with ECULIZUMAB
0.3%
of all ECULIZUMAB reports
7
Deaths
33
Hospitalizations
How Dangerous Is Iron overload From ECULIZUMAB?
Of the 137 reports, 7 (5.1%) resulted in death, 33 (24.1%) required hospitalization, and 5 (3.6%) were considered life-threatening.
Is Iron overload Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 137 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Iron overload?
RUXOLITINIB (135)
DEFERASIROX (132)
CYCLOSPORINE (42)
FERRIC CARBOXYMALTOSE (36)
ERYTHROPOIETIN (31)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (26)
TACROLIMUS (24)
IRON SUCROSE (23)
MYCOPHENOLATE MOFETIL (23)
PREDNISOLONE (22)
Which ECULIZUMAB Alternatives Have Lower Iron overload Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB