Iron overload: Which Medications Cause It? (811 Reports Across 61 Drugs)
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Iron overload has been reported as an adverse event with 61 different drugs in the FDA's FAERS database, with 811 total reports. 110 of these reports resulted in death.The drugs most commonly associated with Iron overload are ECULIZUMAB, RUXOLITINIB, and DEFERASIROX.
811
Total Reports
61
Drugs Involved
110
Deaths
267
Hospitalizations
51.2 yrs
Average Patient Age
50.3% / 49.7%
Female / Male
Which Drugs Cause Iron overload Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ECULIZUMAB | 137 | 0.3% | 7 | 33 | 5 |
| RUXOLITINIB | 135 | 0.2% | 22 | 48 | 4 |
| DEFERASIROX | 132 | 1.2% | 26 | 49 | 4 |
| CYCLOSPORINE | 42 | 0.1% | 4 | 9 | 3 |
| FERRIC CARBOXYMALTOSE | 36 | 0.4% | 4 | 11 | 0 |
| ERYTHROPOIETIN | 31 | 0.4% | 0 | 5 | 0 |
| LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN | 26 | 0.3% | 1 | 5 | 3 |
| TACROLIMUS | 24 | 0.0% | 0 | 3 | 1 |
| IRON SUCROSE | 23 | 0.5% | 0 | 3 | 0 |
| MYCOPHENOLATE MOFETIL | 23 | 0.0% | 0 | 1 | 1 |
| PREDNISOLONE | 22 | 0.0% | 1 | 3 | 1 |
| AZACITIDINE | 21 | 0.1% | 4 | 8 | 0 |
| DARBEPOETIN ALFA | 19 | 0.1% | 7 | 8 | 0 |
| LENALIDOMIDE | 19 | 0.0% | 1 | 2 | 0 |
| ALBENDAZOLE | 18 | 1.7% | 0 | 0 | 1 |
| BUDESONIDE | 18 | 0.1% | 0 | 0 | 1 |
| URSODIOL | 18 | 0.5% | 0 | 0 | 1 |
| DEFERIPRONE | 15 | 0.6% | 6 | 5 | 0 |
| DEFEROXAMINE | 15 | 1.8% | 4 | 3 | 1 |
| SOLIRIS | 15 | 0.6% | 1 | 3 | 0 |