Does ECULIZUMAB Cause Mitral valve incompetence? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Mitral valve incompetence have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
28
Reports of Mitral valve incompetence with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
5
Deaths
16
Hospitalizations
How Dangerous Is Mitral valve incompetence From ECULIZUMAB?
Of the 28 reports, 5 (17.9%) resulted in death, 16 (57.1%) required hospitalization, and 8 (28.6%) were considered life-threatening.
Is Mitral valve incompetence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Mitral valve incompetence?
SACUBITRIL\VALSARTAN (437)
BISOPROLOL (370)
ASPIRIN (282)
FENFLURAMINE (276)
PANTOPRAZOLE (264)
FUROSEMIDE (252)
ATORVASTATIN (222)
ADALIMUMAB (212)
VALSARTAN (185)
AMLODIPINE (178)
Which ECULIZUMAB Alternatives Have Lower Mitral valve incompetence Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB