Mitral valve incompetence: Which Medications Cause It? (5,894 Reports Across 427 Drugs)
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Mitral valve incompetence has been reported as an adverse event with 427 different drugs in the FDA's FAERS database, with 5,894 total reports. 633 of these reports resulted in death.The drugs most commonly associated with Mitral valve incompetence are SACUBITRIL\VALSARTAN, BISOPROLOL, and ASPIRIN.
5,894
Total Reports
427
Drugs Involved
633
Deaths
3,415
Hospitalizations
57.9 yrs
Average Patient Age
53.9% / 46.1%
Female / Male
Which Drugs Cause Mitral valve incompetence Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| SACUBITRIL\VALSARTAN | 437 | 0.4% | 55 | 281 | 15 |
| BISOPROLOL | 370 | 1.3% | 34 | 274 | 7 |
| ASPIRIN | 282 | 0.3% | 33 | 224 | 2 |
| FENFLURAMINE | 276 | 7.0% | 1 | 58 | 4 |
| PANTOPRAZOLE | 264 | 0.3% | 31 | 224 | 8 |
| FUROSEMIDE | 252 | 0.5% | 12 | 165 | 21 |
| ATORVASTATIN | 222 | 0.3% | 32 | 139 | 3 |
| ADALIMUMAB | 212 | 0.0% | 15 | 170 | 22 |
| VALSARTAN | 185 | 0.9% | 11 | 139 | 11 |
| AMLODIPINE | 178 | 0.3% | 6 | 136 | 9 |
| CLOZAPINE | 178 | 0.2% | 5 | 70 | 5 |
| METHOTREXATE | 176 | 0.1% | 27 | 107 | 13 |
| RAMIPRIL | 175 | 0.5% | 27 | 145 | 4 |
| TORSEMIDE | 175 | 2.1% | 30 | 162 | 1 |
| METFORMIN | 173 | 0.2% | 2 | 105 | 3 |
| CYCLOPHOSPHAMIDE | 171 | 0.1% | 26 | 93 | 42 |
| AMIODARONE | 168 | 0.7% | 9 | 127 | 18 |
| TRASTUZUMAB | 167 | 0.4% | 6 | 57 | 17 |
| APIXABAN | 159 | 0.1% | 7 | 90 | 17 |
| CLOPIDOGREL BISULFATE | 154 | 0.3% | 26 | 143 | 0 |