Does METHOTREXATE Cause Mitral valve incompetence? 176 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 176 reports of Mitral valve incompetence have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
176
Reports of Mitral valve incompetence with METHOTREXATE
0.1%
of all METHOTREXATE reports
27
Deaths
107
Hospitalizations
How Dangerous Is Mitral valve incompetence From METHOTREXATE?
Of the 176 reports, 27 (15.3%) resulted in death, 107 (60.8%) required hospitalization, and 13 (7.4%) were considered life-threatening.
Is Mitral valve incompetence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 176 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Mitral valve incompetence?
SACUBITRIL\VALSARTAN (437)
BISOPROLOL (370)
ASPIRIN (282)
FENFLURAMINE (276)
PANTOPRAZOLE (264)
FUROSEMIDE (252)
ATORVASTATIN (222)
ADALIMUMAB (212)
VALSARTAN (185)
AMLODIPINE (178)
Which METHOTREXATE Alternatives Have Lower Mitral valve incompetence Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA