Does ECULIZUMAB Cause Pancytopenia? 176 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 176 reports of Pancytopenia have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.4% of all adverse event reports for ECULIZUMAB.
176
Reports of Pancytopenia with ECULIZUMAB
0.4%
of all ECULIZUMAB reports
30
Deaths
82
Hospitalizations
How Dangerous Is Pancytopenia From ECULIZUMAB?
Of the 176 reports, 30 (17.0%) resulted in death, 82 (46.6%) required hospitalization, and 17 (9.7%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 176 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which ECULIZUMAB Alternatives Have Lower Pancytopenia Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB