Does ECULIZUMAB Cause Transplant failure? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Transplant failure have been filed in association with ECULIZUMAB (SOLIRIS). This represents 0.1% of all adverse event reports for ECULIZUMAB.
40
Reports of Transplant failure with ECULIZUMAB
0.1%
of all ECULIZUMAB reports
6
Deaths
9
Hospitalizations
How Dangerous Is Transplant failure From ECULIZUMAB?
Of the 40 reports, 6 (15.0%) resulted in death, 9 (22.5%) required hospitalization, and 2 (5.0%) were considered life-threatening.
Is Transplant failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ECULIZUMAB. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does ECULIZUMAB Cause?
Fatigue (4,858)
Off label use (4,228)
Haemoglobin decreased (3,028)
Headache (2,699)
Death (2,221)
Pyrexia (1,948)
Dyspnoea (1,819)
Asthenia (1,732)
Drug ineffective (1,644)
Nausea (1,579)
What Other Drugs Cause Transplant failure?
TACROLIMUS (559)
MYCOPHENOLATE MOFETIL (436)
CYCLOPHOSPHAMIDE (221)
FLUDARABINE (218)
PREDNISONE (182)
CYCLOSPORINE (180)
PREDNISOLONE (172)
BUSULFAN (147)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (113)
AUTOLOGOUS CULTURED CHONDROCYTES (108)
Which ECULIZUMAB Alternatives Have Lower Transplant failure Risk?
ECULIZUMAB vs EDARAVONE
ECULIZUMAB vs EDETATE
ECULIZUMAB vs EDOXABAN
ECULIZUMAB vs EDOXABAN TOSILATE
ECULIZUMAB vs EFALIZUMAB