Transplant failure: Which Medications Cause It? (1,681 Reports Across 116 Drugs)
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Transplant failure has been reported as an adverse event with 116 different drugs in the FDA's FAERS database, with 1,681 total reports. 543 of these reports resulted in death.The drugs most commonly associated with Transplant failure are TACROLIMUS, MYCOPHENOLATE MOFETIL, and CYCLOPHOSPHAMIDE.
1,681
Total Reports
116
Drugs Involved
543
Deaths
491
Hospitalizations
42.9 yrs
Average Patient Age
40.6% / 59.4%
Female / Male
Which Drugs Cause Transplant failure Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TACROLIMUS | 559 | 0.6% | 196 | 239 | 88 |
| MYCOPHENOLATE MOFETIL | 436 | 0.6% | 143 | 168 | 67 |
| CYCLOPHOSPHAMIDE | 221 | 0.2% | 71 | 42 | 11 |
| FLUDARABINE | 218 | 0.9% | 72 | 50 | 14 |
| PREDNISONE | 182 | 0.1% | 110 | 71 | 36 |
| CYCLOSPORINE | 180 | 0.3% | 86 | 45 | 30 |
| PREDNISOLONE | 172 | 0.2% | 67 | 80 | 29 |
| BUSULFAN | 147 | 1.3% | 47 | 39 | 11 |
| LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN | 113 | 1.2% | 35 | 37 | 12 |
| AUTOLOGOUS CULTURED CHONDROCYTES | 108 | 57.5% | 0 | 0 | 0 |
| RITUXIMAB | 102 | 0.1% | 50 | 21 | 11 |
| METHYLPREDNISOLONE | 95 | 0.2% | 38 | 33 | 17 |
| ALEMTUZUMAB | 84 | 0.6% | 23 | 35 | 20 |
| BASILIXIMAB | 78 | 1.1% | 29 | 34 | 12 |
| METHOTREXATE | 68 | 0.0% | 31 | 28 | 15 |
| MYCOPHENOLIC ACID | 68 | 0.4% | 18 | 27 | 9 |
| SIROLIMUS | 66 | 0.6% | 14 | 27 | 19 |
| MELPHALAN | 52 | 0.3% | 18 | 7 | 1 |
| THYMOCYTE IMMUNE GLOBULIN NOS | 49 | 0.9% | 16 | 14 | 3 |
| THIOTEPA | 45 | 0.7% | 12 | 19 | 2 |