EMAPALUMAB for Still's disease: Side Effects & Safety Data
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There are 14 adverse event reports in the FDA FAERS database where EMAPALUMAB was used for Still's disease.
Most Reported Side Effects for EMAPALUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 67 | 38.7% | 22 | 45 |
| Condition aggravated | 37 | 21.4% | 6 | 24 |
| Drug ineffective | 37 | 21.4% | 14 | 24 |
| Haemophagocytic lymphohistiocytosis | 33 | 19.1% | 8 | 21 |
| Multiple organ dysfunction syndrome | 22 | 12.7% | 18 | 18 |
| Staphylococcal bacteraemia | 17 | 9.8% | 1 | 1 |
| Adrenal insufficiency | 14 | 8.1% | 0 | 13 |
| Drug reaction with eosinophilia and systemic symptoms | 14 | 8.1% | 0 | 13 |
| Respiratory failure | 14 | 8.1% | 4 | 12 |
| Pyrexia | 12 | 6.9% | 0 | 7 |
| Disseminated mucormycosis | 11 | 6.4% | 11 | 11 |
| Disseminated intravascular coagulation | 10 | 5.8% | 10 | 10 |
| Acute kidney injury | 9 | 5.2% | 0 | 9 |
| Clostridium difficile infection | 9 | 5.2% | 0 | 9 |
| Cytomegalovirus infection | 9 | 5.2% | 2 | 7 |
Other Indications for EMAPALUMAB
Haemophagocytic lymphohistiocytosis (119)
Familial haemophagocytic lymphohistiocytosis (21)
Product used for unknown indication (10)
Epstein-barr virus infection (7)
Prophylaxis (7)
Other Drugs Used for Still's disease
CANAKINUMAB (1,847)
ANAKINRA (1,563)
TOCILIZUMAB (1,418)
METHOTREXATE (703)
CYCLOSPORINE (387)
PREDNISOLONE (384)
PREDNISONE (328)
METHYLPREDNISOLONE (275)
ETANERCEPT (202)
INFLIXIMAB (181)