EMAPALUMAB for Prophylaxis: Side Effects & Safety Data
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There are 7 adverse event reports in the FDA FAERS database where EMAPALUMAB was used for Prophylaxis.
Most Reported Side Effects for EMAPALUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 67 | 38.7% | 22 | 45 |
| Condition aggravated | 37 | 21.4% | 6 | 24 |
| Drug ineffective | 37 | 21.4% | 14 | 24 |
| Haemophagocytic lymphohistiocytosis | 33 | 19.1% | 8 | 21 |
| Multiple organ dysfunction syndrome | 22 | 12.7% | 18 | 18 |
| Staphylococcal bacteraemia | 17 | 9.8% | 1 | 1 |
| Adrenal insufficiency | 14 | 8.1% | 0 | 13 |
| Drug reaction with eosinophilia and systemic symptoms | 14 | 8.1% | 0 | 13 |
| Respiratory failure | 14 | 8.1% | 4 | 12 |
| Pyrexia | 12 | 6.9% | 0 | 7 |
| Disseminated mucormycosis | 11 | 6.4% | 11 | 11 |
| Disseminated intravascular coagulation | 10 | 5.8% | 10 | 10 |
| Acute kidney injury | 9 | 5.2% | 0 | 9 |
| Clostridium difficile infection | 9 | 5.2% | 0 | 9 |
| Cytomegalovirus infection | 9 | 5.2% | 2 | 7 |
Other Indications for EMAPALUMAB
Haemophagocytic lymphohistiocytosis (119)
Familial haemophagocytic lymphohistiocytosis (21)
Still's disease (14)
Product used for unknown indication (10)
Epstein-barr virus infection (7)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)