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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Prophylaxis: Which Medications Are Safest? (2,169 Drugs Compared)

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2,169 medications are used for Prophylaxis, with 68,508 combined adverse event reports. The most reported drugs for Prophylaxis are PEGFILGRASTIM and HUMAN C1-ESTERASE INHIBITOR.

68,508
Total Reports
2,169
Drugs Used

All Medications for Prophylaxis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PEGFILGRASTIM ZIEXTENZO 7,424 2,367 7,050 2.9%
HUMAN C1-ESTERASE INHIBITOR Cinryze 5,950 1,403 3,966 9.8%
DENOSUMAB Bilprevda 4,541 19,354 17,749 13.0%
SULFAMETHOXAZOLE\TRIMETHOPRIM - 3,197 5,777 19,426 14.9%
ASPIRIN Aspirin 2,083 13,029 53,089 14.1%
VALACYCLOVIR Valacyclovir Hydrochloride 1,574 812 6,169 6.2%
PANTOPRAZOLE Pantoprazole Sodium 1,502 9,456 23,952 12.0%
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN VARIVAX 1,444 79 265 3.9%
CLOPIDOGREL BISULFATE Clopidogrel 1,296 5,327 24,774 11.6%
ENOXAPARIN Enoxaparin Sodium 1,278 3,423 10,898 13.7%
ATORVASTATIN Atorvastatin calcium 1,253 4,992 24,078 6.3%
FILGRASTIM NYPOZI txid 1,197 3,295 4,712 22.1%
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT - 1,107 367 2,090 3.5%
DEFIBROTIDE DEFITELIO 1,073 1,804 832 48.2%
NEULASTA - 1,012 471 769 32.0%
OMEPRAZOLE omeprazole sodium bicarbonate 985 8,515 19,847 9.8%
DEXAMETHASONE Dexamethasone Sodium Phosphate 926 22,319 51,311 17.8%
METHOTREXATE Methotrexate 856 21,265 68,793 8.4%
WATER Sterile Diluent for Treprostinil 855 206 610 4.4%
ACYCLOVIR Acyclovir 834 2,057 6,095 14.5%

View all 2,169 drugs →

Most Reported Drugs for Prophylaxis

#1 most reported
#2 most reported
#3 most reported