FILGRASTIM for Prophylaxis: Side Effects & Safety Data
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There are 1,197 adverse event reports in the FDA FAERS database where FILGRASTIM was used for Prophylaxis.
Most Reported Side Effects for FILGRASTIM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,930 | 13.0% | 387 | 578 |
| Febrile neutropenia | 1,570 | 10.5% | 336 | 848 |
| Neutropenia | 1,431 | 9.6% | 277 | 419 |
| Death | 1,213 | 8.2% | 1,209 | 230 |
| Pyrexia | 1,085 | 7.3% | 200 | 618 |
| Diarrhoea | 739 | 5.0% | 196 | 326 |
| Nausea | 718 | 4.8% | 152 | 335 |
| Bone pain | 706 | 4.7% | 53 | 334 |
| Thrombocytopenia | 697 | 4.7% | 199 | 269 |
| Anaemia | 626 | 4.2% | 176 | 290 |
| Drug ineffective | 614 | 4.1% | 174 | 231 |
| Fatigue | 581 | 3.9% | 118 | 264 |
| Pneumonia | 562 | 3.8% | 319 | 252 |
| Sepsis | 543 | 3.7% | 375 | 234 |
| Vomiting | 520 | 3.5% | 141 | 243 |
Other Indications for FILGRASTIM
Product used for unknown indication (4,036)
Neutropenia (2,010)
Haematopoietic stem cell mobilisation (988)
Acute lymphocytic leukaemia (619)
Febrile neutropenia (380)
Acute myeloid leukaemia (344)
Off label use (253)
Autologous haematopoietic stem cell transplant (193)
B-cell lymphoma (191)
White blood cell count decreased (177)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)