Does EPLERENONE Cause Hyperkalaemia? 248 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 248 reports of Hyperkalaemia have been filed in association with EPLERENONE (Inspra). This represents 6.6% of all adverse event reports for EPLERENONE.
248
Reports of Hyperkalaemia with EPLERENONE
6.6%
of all EPLERENONE reports
14
Deaths
163
Hospitalizations
How Dangerous Is Hyperkalaemia From EPLERENONE?
Of the 248 reports, 14 (5.6%) resulted in death, 163 (65.7%) required hospitalization, and 42 (16.9%) were considered life-threatening.
Is Hyperkalaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for EPLERENONE. However, 248 reports have been filed with the FAERS database.
What Other Side Effects Does EPLERENONE Cause?
Acute kidney injury (570)
Hypotension (398)
Dyspnoea (395)
Cardiac failure (338)
Oedema peripheral (268)
Dizziness (248)
Drug ineffective (244)
Fatigue (202)
Off label use (188)
Nausea (170)
What Other Drugs Cause Hyperkalaemia?
METFORMIN (2,565)
SPIRONOLACTONE (2,518)
FUROSEMIDE (2,035)
RAMIPRIL (1,383)
SACUBITRIL\VALSARTAN (1,192)
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036)
LISINOPRIL (948)
POTASSIUM (944)
BISOPROLOL (850)
TACROLIMUS (713)
Which EPLERENONE Alternatives Have Lower Hyperkalaemia Risk?
EPLERENONE vs EPLONTERSEN
EPLERENONE vs EPOETIN ALFA-EPBX
EPLERENONE vs EPOGEN
EPLERENONE vs EPOPROSTENOL
EPLERENONE vs EPTIFIBATIDE