Does FLUOROURACIL Cause Colitis? 449 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 449 reports of Colitis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.9% of all adverse event reports for FLUOROURACIL.
449
Reports of Colitis with FLUOROURACIL
0.9%
of all FLUOROURACIL reports
49
Deaths
341
Hospitalizations
How Dangerous Is Colitis From FLUOROURACIL?
Of the 449 reports, 49 (10.9%) resulted in death, 341 (75.9%) required hospitalization, and 59 (13.1%) were considered life-threatening.
Is Colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 449 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Colitis?
ADALIMUMAB (3,043)
NIVOLUMAB (2,123)
IPILIMUMAB (1,988)
PEMBROLIZUMAB (1,638)
INFLIXIMAB (1,254)
METHOTREXATE (1,166)
PREDNISONE (1,100)
VEDOLIZUMAB (1,077)
CARBOPLATIN (993)
MESALAMINE (839)
Which FLUOROURACIL Alternatives Have Lower Colitis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE