Does FLUOROURACIL Cause Endocarditis? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Endocarditis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.1% of all adverse event reports for FLUOROURACIL.
35
Reports of Endocarditis with FLUOROURACIL
0.1%
of all FLUOROURACIL reports
15
Deaths
30
Hospitalizations
How Dangerous Is Endocarditis From FLUOROURACIL?
Of the 35 reports, 15 (42.9%) resulted in death, 30 (85.7%) required hospitalization, and 5 (14.3%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which FLUOROURACIL Alternatives Have Lower Endocarditis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE