Does FLUOROURACIL Cause Leukopenia? 1,287 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,287 reports of Leukopenia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 2.4% of all adverse event reports for FLUOROURACIL.
1,287
Reports of Leukopenia with FLUOROURACIL
2.4%
of all FLUOROURACIL reports
107
Deaths
307
Hospitalizations
How Dangerous Is Leukopenia From FLUOROURACIL?
Of the 1,287 reports, 107 (8.3%) resulted in death, 307 (23.9%) required hospitalization, and 81 (6.3%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 1,287 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which FLUOROURACIL Alternatives Have Lower Leukopenia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE