Does FLUOROURACIL Cause Myocarditis? 124 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 124 reports of Myocarditis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.2% of all adverse event reports for FLUOROURACIL.
124
Reports of Myocarditis with FLUOROURACIL
0.2%
of all FLUOROURACIL reports
13
Deaths
94
Hospitalizations
How Dangerous Is Myocarditis From FLUOROURACIL?
Of the 124 reports, 13 (10.5%) resulted in death, 94 (75.8%) required hospitalization, and 39 (31.5%) were considered life-threatening.
Is Myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 124 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Myocarditis?
CLOZAPINE (1,702)
PEMBROLIZUMAB (1,060)
NIVOLUMAB (959)
IPILIMUMAB (475)
OLANZAPINE (425)
ATEZOLIZUMAB (372)
CARBOPLATIN (325)
QUETIAPINE (315)
MESALAMINE (272)
BEVACIZUMAB (230)
Which FLUOROURACIL Alternatives Have Lower Myocarditis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE