Does FLUOROURACIL Cause Pneumonitis? 227 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 227 reports of Pneumonitis have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.4% of all adverse event reports for FLUOROURACIL.
227
Reports of Pneumonitis with FLUOROURACIL
0.4%
of all FLUOROURACIL reports
92
Deaths
126
Hospitalizations
How Dangerous Is Pneumonitis From FLUOROURACIL?
Of the 227 reports, 92 (40.5%) resulted in death, 126 (55.5%) required hospitalization, and 32 (14.1%) were considered life-threatening.
Is Pneumonitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 227 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Pneumonitis?
NIVOLUMAB (2,076)
PEMBROLIZUMAB (1,933)
METHOTREXATE (1,188)
PACLITAXEL (1,110)
CARBOPLATIN (975)
EVEROLIMUS (919)
IPILIMUMAB (891)
ATEZOLIZUMAB (842)
DURVALUMAB (827)
RITUXIMAB (747)
Which FLUOROURACIL Alternatives Have Lower Pneumonitis Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE