GILTERITINIB for Flt3 gene mutation: Side Effects & Safety Data
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There are 210 adverse event reports in the FDA FAERS database where GILTERITINIB was used for Flt3 gene mutation.
Most Reported Side Effects for GILTERITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Acute myeloid leukaemia | 366 | 10.0% | 247 | 120 |
| Febrile neutropenia | 346 | 9.4% | 115 | 235 |
| Off label use | 334 | 9.1% | 79 | 104 |
| Platelet count decreased | 327 | 8.9% | 61 | 139 |
| Pneumonia | 302 | 8.2% | 133 | 192 |
| Myelosuppression | 300 | 8.2% | 75 | 114 |
| Pyrexia | 281 | 7.7% | 84 | 193 |
| Death | 206 | 5.6% | 206 | 52 |
| Product use issue | 189 | 5.2% | 55 | 50 |
| Hepatic function abnormal | 181 | 4.9% | 61 | 93 |
| Neutrophil count decreased | 162 | 4.4% | 35 | 60 |
| Acute myeloid leukaemia recurrent | 155 | 4.2% | 39 | 44 |
| Anaemia | 154 | 4.2% | 37 | 75 |
| Infection | 153 | 4.2% | 76 | 89 |
| Cytopenia | 152 | 4.1% | 32 | 36 |
Other Indications for GILTERITINIB
Acute myeloid leukaemia (1,963)
Acute myeloid leukaemia recurrent (669)
Acute myeloid leukaemia refractory (548)
Product used for unknown indication (511)
Acute myeloid leukaemia (in remission) (21)
Acute monocytic leukaemia (20)
Acute leukaemia (19)
Leukaemia (17)
Acute myelomonocytic leukaemia (16)
Chronic myelomonocytic leukaemia (15)