MIDOSTAURIN for Flt3 gene mutation: Side Effects & Safety Data
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There are 16 adverse event reports in the FDA FAERS database where MIDOSTAURIN was used for Flt3 gene mutation.
Most Reported Side Effects for MIDOSTAURIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 397 | 13.3% | 396 | 22 |
| Nausea | 252 | 8.4% | 21 | 50 |
| Febrile neutropenia | 223 | 7.5% | 33 | 90 |
| Diarrhoea | 194 | 6.5% | 29 | 59 |
| Pyrexia | 188 | 6.3% | 25 | 90 |
| Acute myeloid leukaemia recurrent | 171 | 5.7% | 29 | 14 |
| Pancytopenia | 152 | 5.1% | 11 | 25 |
| Vomiting | 152 | 5.1% | 25 | 45 |
| Drug ineffective | 151 | 5.1% | 18 | 13 |
| Thrombocytopenia | 140 | 4.7% | 17 | 37 |
| Neutropenia | 136 | 4.5% | 15 | 25 |
| Pneumonia | 128 | 4.3% | 47 | 74 |
| Bone marrow failure | 109 | 3.6% | 13 | 14 |
| Sepsis | 106 | 3.5% | 54 | 50 |
| Anaemia | 97 | 3.2% | 17 | 33 |
Other Indications for MIDOSTAURIN
Acute myeloid leukaemia (1,653)
Product used for unknown indication (688)
Systemic mastocytosis (270)
Myelodysplastic syndrome (45)
Mastocytic leukaemia (36)
Mastocytosis (36)
Leukaemia (28)
Acute leukaemia (15)
Myeloid leukaemia (14)
Malignant mast cell neoplasm (13)