Does MIDOSTAURIN Cause Pancytopenia? 152 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 152 reports of Pancytopenia have been filed in association with MIDOSTAURIN (RYDAPT). This represents 5.1% of all adverse event reports for MIDOSTAURIN.
152
Reports of Pancytopenia with MIDOSTAURIN
5.1%
of all MIDOSTAURIN reports
11
Deaths
25
Hospitalizations
How Dangerous Is Pancytopenia From MIDOSTAURIN?
Of the 152 reports, 11 (7.2%) resulted in death, 25 (16.4%) required hospitalization, and 9 (5.9%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MIDOSTAURIN. However, 152 reports have been filed with the FAERS database.
What Other Side Effects Does MIDOSTAURIN Cause?
Death (397)
Nausea (252)
Febrile neutropenia (223)
Diarrhoea (194)
Pyrexia (188)
Acute myeloid leukaemia recurrent (171)
Vomiting (152)
Drug ineffective (151)
Thrombocytopenia (140)
Neutropenia (136)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which MIDOSTAURIN Alternatives Have Lower Pancytopenia Risk?
MIDOSTAURIN vs MIFEPRISTONE
MIDOSTAURIN vs MIGALASTAT
MIDOSTAURIN vs MIGLITOL
MIDOSTAURIN vs MIGLUSTAT
MIDOSTAURIN vs MILNACIPRAN