Does MIDOSTAURIN Cause Neutropenia? 136 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 136 reports of Neutropenia have been filed in association with MIDOSTAURIN (RYDAPT). This represents 4.5% of all adverse event reports for MIDOSTAURIN.
136
Reports of Neutropenia with MIDOSTAURIN
4.5%
of all MIDOSTAURIN reports
15
Deaths
25
Hospitalizations
How Dangerous Is Neutropenia From MIDOSTAURIN?
Of the 136 reports, 15 (11.0%) resulted in death, 25 (18.4%) required hospitalization, and 23 (16.9%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for MIDOSTAURIN.
What Other Side Effects Does MIDOSTAURIN Cause?
Death (397)
Nausea (252)
Febrile neutropenia (223)
Diarrhoea (194)
Pyrexia (188)
Acute myeloid leukaemia recurrent (171)
Pancytopenia (152)
Vomiting (152)
Drug ineffective (151)
Thrombocytopenia (140)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which MIDOSTAURIN Alternatives Have Lower Neutropenia Risk?
MIDOSTAURIN vs MIFEPRISTONE
MIDOSTAURIN vs MIGALASTAT
MIDOSTAURIN vs MIGLITOL
MIDOSTAURIN vs MIGLUSTAT
MIDOSTAURIN vs MILNACIPRAN