Does GIVOSIRAN Cause Asthenia? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Asthenia have been filed in association with GIVOSIRAN (GIVLAARI). This represents 2.2% of all adverse event reports for GIVOSIRAN.
27
Reports of Asthenia with GIVOSIRAN
2.2%
of all GIVOSIRAN reports
0
Deaths
11
Hospitalizations
How Dangerous Is Asthenia From GIVOSIRAN?
Of the 27 reports, 11 (40.7%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Asthenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GIVOSIRAN. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does GIVOSIRAN Cause?
Porphyria acute (381)
Hospitalisation (141)
Nausea (91)
Product dose omission issue (85)
Fatigue (84)
Therapy interrupted (83)
Pain (74)
Intentional dose omission (63)
Abdominal pain (62)
Vomiting (58)
What Other Drugs Cause Asthenia?
ADALIMUMAB (9,797)
LENALIDOMIDE (8,192)
METHOTREXATE (6,269)
ETANERCEPT (5,546)
RITUXIMAB (5,489)
PREDNISONE (4,794)
TOCILIZUMAB (3,898)
INFLIXIMAB (3,729)
LEVOTHYROXINE (3,694)
SACUBITRIL\VALSARTAN (3,667)
Which GIVOSIRAN Alternatives Have Lower Asthenia Risk?
GIVOSIRAN vs GLASDEGIB
GIVOSIRAN vs GLATIRAMER
GIVOSIRAN vs GLECAPREVIR\PIBRENTASVIR
GIVOSIRAN vs GLEEVEC
GIVOSIRAN vs GLICLAZIDE