Does METHOTREXATE Cause Asthenia? 6,269 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6,269 reports of Asthenia have been filed in association with METHOTREXATE (Methotrexate). This represents 2.5% of all adverse event reports for METHOTREXATE.
6,269
Reports of Asthenia with METHOTREXATE
2.5%
of all METHOTREXATE reports
1,353
Deaths
2,817
Hospitalizations
How Dangerous Is Asthenia From METHOTREXATE?
Of the 6,269 reports, 1,353 (21.6%) resulted in death, 2,817 (44.9%) required hospitalization, and 1,603 (25.6%) were considered life-threatening.
Is Asthenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 6,269 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Asthenia?
ADALIMUMAB (9,797)
LENALIDOMIDE (8,192)
ETANERCEPT (5,546)
RITUXIMAB (5,489)
PREDNISONE (4,794)
TOCILIZUMAB (3,898)
INFLIXIMAB (3,729)
LEVOTHYROXINE (3,694)
SACUBITRIL\VALSARTAN (3,667)
PALBOCICLIB (3,660)
Which METHOTREXATE Alternatives Have Lower Asthenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA